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ea0007p66 | Diabetes, metabolism and cardiovascular | BES2004

Testosterone-induced vasodilatation of isolated human mesenteric and pulmonary resistance arteries is independent of the vascular endothelium

Jones R , Rowell K , Pugh P , Shorthouse A , Adam I , Vaughan R , Rocco G , Hopkinson D , Channer K , Jones T

Testosterone reduces myocardial ischaemia in men with coronary artery disease, and improves symptoms and exercise capacity in men with heart failure, effects proposed to be due to testosterone-induced coronary, systemic and pulmonary vasodilatation. Endothelial-independent calcium channel antagonism is proposed as the effector mechanism from in vitro animal studies, but this has yet to be confirmed in humans.In the present study we have investigated the ...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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